An ebastine metabolite; metabolized by CYP2J2 and CYP3A4 to form carabastine

Hydroxyebastine – 500 µg

Brand:
Cayman
CAS:
210686-41-2
Storage:
-20
UN-No:
Non-Hazardous - /

Hydroxyebastine is an ebastine (Item No. 15372) metabolite.{24986,34756} Ebastine undergoes rapid first-pass metabolism by the cytochrome P450 isoform CYP2J2 to form hydroxyebastine which is then metabolized by CYP2J2 and CYP3A4 to form carebastine.  

 

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Description

An ebastine metabolite; metabolized by CYP2J2 and CYP3A4 to form carabastine

Formal name: 4-[4-(diphenylmethoxy)-1-piperidinyl]-1-[4-(2-hydroxy-1,1-dimethylethyl)phenyl]-1-butanone

Synonyms: 

Molecular weight: 485.7

CAS: 210686-41-2

Purity: ≥87%

Formulation: A solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Allergy||Research Area|Toxicology|Drug Metabolism|Cytochrome P450||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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