Immunogen: Recombinant human HO-1 (Hsp32) • Host: Rabbit • Species reactivity: (+) Human • Applications: ELISA

HO-1 (Hsp32) Polyclonal Antibody – 500 µg

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Cayman
Storage:

Heme oxygenase-1 (HO-1), also known as heat shock protein 32 (Hsp32), is an inducible heme oxygenase encoded by the HMOX1 gene.{40053,40052,38123} It is a membrane-bound enzyme that catalyzes the cleavage of heme to release carbon monoxide (CO), ferrous ions (Fe2+), and biliverdin, with biliverdin being further processed into bilirubin. HO-1 is found in human spleen, liver, and kidney where its expression is induced by the presence of heme, hormones, metals, oxidative agents, and therapeutic compounds to protect against oxidative stress and inflammatory responses. HO-1 is upregulated in a variety of cancers and siRNA knockdown of HMOX1 or inhibition of HO-1 decreases cancer cell proliferation.{38124,38125,38126} HO-1 also interacts with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accessory protein Orf3a that, in a similar virus, SARS-CoV, is associated with activation of the NLRP3 inflammasome.{55024,55036,55037} Cayman’s HO-1 (Hsp32) Polyclonal Antibody can be used for ELISA, immunofluorescence (IF), immunohistochemistry (IHC), and Western blot (WB) applications. The antibody recognizes HO-1 (Hsp32) at approximately 32 kDa from human samples.  

 

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SKU: 24633 - 500 µg Category:

Description

Immunogen: Recombinant human HO-1 (Hsp32) • Host: Rabbit • Species reactivity: (+) Human • Applications: ELISA, IF, IHC, and WB • MW: ~32 kDa

Synonyms: Heat Shock Protein 32|Heme Oxygenase-1|HMOX1

Immunogen: Human recombinant HO-1 (Hsp32)

Formulation: 500 µg of Protein A-purified HO-1 (Hsp32) polyclonal antibody

Isotype:

Applications: ELISA, IF, IHC, and WB

Origin:

Stability: 365 days

Application|ELISA||Application|Immunofluorescence||Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cancer||Research Area|Cell Biology|Cellular Chaperones||Research Area|Immunology & Inflammation|Pulmonary Diseases|COVID-19||Research Area|Infectious Disease|Viral Diseases|Coronaviruses||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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