A cell-permeable prodrug form of HNMPA; inhibits IRTK autophosphorylation in CHO cells expressing the human receptor in a concentration- and time-dependent manner; inhibits 2-deoxyglucose uptake but does not affect insulin-stimulated thymidine uptake in CHO cells (≤100 μM)

HNMPA-(AM)3 – 1 mg

Brand:
Cayman
CAS:
120944-03-8
Storage:
-20
UN-No:
- 1170 / 3

HNMPA-(AM)3 is a cell-permeable prodrug form of the insulin receptor tyrosine kinase (IRTK) inhibitor HNMPA (Item No. 15543).{25668} HNMPA-(AM)3 inhibits IRTK autophosphorylation in CHO cells expressing the human receptor in a concentration- and time-dependent manner. It inhibits 2-deoxyglucose uptake but does not affect insulin-stimulated thymidine uptake in CHO cells at concentrations up to 100 μM.  

 

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SKU: 23245 - 1 mg Category:

Description

A cell-permeable prodrug form of HNMPA; inhibits IRTK autophosphorylation in CHO cells expressing the human receptor in a concentration- and time-dependent manner; inhibits 2-deoxyglucose uptake but does not affect insulin-stimulated thymidine uptake in CHO cells (≤100 μM)

Formal name: P-[[(acetyloxy)methoxy]-2-naphthalenylmethyl]-phosphonic acid, bis[(acetyloxy)methyl] ester

Synonyms: 

Molecular weight: 454.4

CAS: 120944-03-8

Purity: ≥95%

Formulation: A solution in ethanol

Product Type|Biochemicals|Kinase Inhibitors|IGF-1R/InsR Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes

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