Description
Histone H3 is a nuclear protein and a component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei.{57056} It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various post-translational modifications (PTMs), including methylation, phosphorylation, acetylation, and citrullination.{57056,53978} Trimethylation of lysine 9 and phosphorylation of serine 10 on histone H3 (H3K9Me3/S10Ph) is associated with repression of polycomb-regulated genes in differentiated mesenchymal stem cells (MSCs) and resting B cells but not pluripotent embryonic stem cells (ESCs).{60015} Cayman’s H3K9Me3/S10Ph Monoclonal Antibody recognizes histone H3 only when modified by both trimethylation at K9 and phosphorylation at S10. This antibody can be used for ELISA, multiplex-based assay, and Western blot (WB) applications.
Synonyms:
Immunogen: Peptide corresponding to H3K9Me3/S10Ph
Formulation: 100 µg of protein A-affinity purified monoclonal antibody
Isotype: IgG
Applications: ELISA, multiplex-based assays, WB
Origin:
Stability: 365 days
Application|ELISA||Application|Multiplex||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cell Biology|Stem Cell Research|Differentiation||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Deacetylation||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Demethylation||Research Area|Epigenetics, Transcription, & Translation|Histones/Histone Peptides|Methylated||Research Area|Epigenetics, Transcription, & Translation|Histones/Histone Peptides|Phosphorylated||Research Area|Epigenetics, Transcription, & Translation|Writers|Histone Methylation||Research Area|Epigenetics, Transcription, & Translation|Writers|Phosphorylation||Research Area|Immunology & Inflammation|Adaptive Immunity
