Description
Histone H3 is a nuclear protein and a component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei.{57056} It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various post-translational modifications (PTMs), including methylation, phosphorylation, acetylation, and citrullination.{57056,53978} Histone H3 lysine 18 (H3K18) is subject to both acetylation and methylation.{60019} An H3K18Me2 (1-21) peptide reduces the association of lamin A/C with chromatin in a chromatin immunoprecipitation (ChIP) assay.{60020} Dimethylation of histone H3 at lysine 18 is increased in patients with diabetes.{60021} Cayman’s Histone H3K18Me2 Monoclonal Antibody can be used for ELISA, multiplex-based assay, and Western blot (WB) applications.
Synonyms: Dimethylated Histone H3 Lysine 18
Immunogen: Peptide corresponding to H3K18Me2
Formulation: 100 µg of protein A-affinity purified antibody
Isotype: IgG
Applications: ELISA, multiplex-based assays, WB
Origin:
Stability: 365 days
Application|ELISA||Application|Multiplex||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Demethylation||Research Area|Epigenetics, Transcription, & Translation|Histones/Histone Peptides|Methylated||Research Area|Epigenetics, Transcription, & Translation|Writers|Histone Methylation
