Antigen: peptide from the C-terminal region of human HIF-1α6 • Host: rabbit • Species Reactivity: (+) human

HIF-1α (C-Term) Polyclonal Antibody – 1 ea

Brand:
Cayman
Storage:

Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor that accumulates under low-oxygen conditions.{10948,11044} Following hypoxic stimulus and cytoplasmic accumulation, HIF-1α migrates to the nucleus where with other transcription factors, it drives the production of stress-adaptive proteins. This response is essential for maintenance of normal oxidative physiology, however overexpression in cancer cells promotes tumor survival.{11044,9833,9834,9835,10695} HIF-1α is an endothelial PAS domain protein 1 (EPAS-1) family member with phosphorylation dependent activities.{11043,10898} Cayman Chemical’s HIF-1α polyclonal antibody can be used for WB analysis for HIF-1α on samples from human, mouse, and simian. It is not suitable for ICC or IP. Other applications for use of this antibody have not yet been tested.  

 

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SKU: 10006421 - 1 ea Category:

Description

Antigen: peptide from the C-terminal region of human HIF-1α6 • Host: rabbit • Species Reactivity: (+) human, mouse, and simian; other species not tested • Applications: IHC, WB

Synonyms: Hypoxia -Inducible Factor-1α

Immunogen: Peptide from the C-terminal region of human HIF-1α

Formulation: 500 µl of peptide affinity-purified antibody

Isotype:

Applications: IHC and WB

Origin: Animal/Rabbit

Stability: 365 days

Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cancer|Transcription Factors|HIF-1α||Research Area|Cancer|Tumor Microenvironment||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors

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