Description
An inhibitor of LRRK2 (IC50 = 20.3 nM); also inhibits G2019S, A2016T, and [G2019S+A2016T] mutants of LRRK2 (IC50s = 3.2, 153, and 95.9 nM, respectively); brain penetrant and inhibits Ser910 and Ser935 phosphorylation of both wild-type and G2019S mutant LRRK2
Formal name: [4-[[5-chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone
Synonyms:
Molecular weight: 377.8
CAS: 1351758-81-0
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Kinase Inhibitors|Other Serine/Threonine Kinases||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Neuroscience
