A prodrug form of 5-aminolevulinic acid; produces equivalent PpIX induction in WiDr and NHIK 3025 carcinoma cells at concentrations approximately 100-fold lower than 5-aminolevulinic acid; penetrates upper skin layers more effectively in pigs and induces higher levels of PpIX fluorescence in nude mice when compared with 5-aminolevulinic acid following topical administration

Hexaminolevulinate (hydrochloride) – 1 g

Brand:
Cayman
CAS:
140898-91-5
Storage:
-20
UN-No:
Non-Hazardous - /

Hexaminolevulinate is a lipophilic, hexyl ester prodrug form of 5-aminolevulinic acid (Item No. 9001902).{40686} It produces equivalent protoporphyrin IX (PpIX) induction in WiDr and NHIK 3025 carcinoma cells at concentrations approximately 100-fold lower than 5-aminolevulinic acid. In vivo, hexaminolevulinate penetrates upper skin layers more effectively in pigs and induces higher levels of PpIX fluorescence in nude mice when compared with 5-aminolevulinic acid following topical administration.{40687} Formulations containing hexaminolevulinate have been used in imaging and photodynamic therapy for a variety of urogenital cancers.  

 

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SKU: 23949 - 1 g Category:

Description

A prodrug form of 5-aminolevulinic acid; produces equivalent PpIX induction in WiDr and NHIK 3025 carcinoma cells at concentrations approximately 100-fold lower than 5-aminolevulinic acid; penetrates upper skin layers more effectively in pigs and induces higher levels of PpIX fluorescence in nude mice when compared with 5-aminolevulinic acid following topical administration

Formal name: 5-amino-4-oxo-pentanoic acid, hexyl ester, monohydrochloride

Synonyms:  5-Aminolevulinic Acid hexyl ester|Hexyl 5- aminolevulinate

Molecular weight: 251.8

CAS: 140898-91-5

Purity: ≥95%

Formulation: A crystalline solid

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cancer

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