A triazole fungicide; inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol; curative against powdery mildew on barley plants at 6.7 mg/L; improves water

Hexaconazole – 50 mg

Brand:
Cayman
CAS:
79983-71-4
Storage:
-20
UN-No:
Non-Hazardous - /

Hexaconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death.{30331} It is fungicidal against the powdery mildews B. graminis and S. cucurbitae on cucumber plants in a concentration-dependent manner and is curative against powdery mildew on barley plants when used at a concentration of 6.7 mg/L.{40985} It also inhibits growth of R. bataticola and S. rolfsii (ED50s = 6.35 and 1.27 mg/L, respectively).{40986} Exogenous application of hexaconazole (15 mg/L) to M. chamomilla plants improves water, proline, and protein contents as well as increases non-enzymatic and enzymatic antioxidant and apigenin-7-glucoside content during a water deficit stress tolerance test.{40987} Hexaconazole inhibits the differentiation of mouse embryonic stem cells into cardiomyocytes (EC50 = 16.6 μM).{40988} It also induces bone morphological defects in mouse fetuses when administered to pregnant adult females during gestation.  

 

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SKU: 24118 - 50 mg Category:

Description

A triazole fungicide; inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol; curative against powdery mildew on barley plants at 6.7 mg/L; improves water, proline, and protein contents as well as increases non-enzymatic and enzymatic antioxidant and apigenin-7-glucoside content in M. chamomilla plants during a water deficit stress tolerance test at 15 mg/L; inhibits the differentiation of mouse embryonic stem cells into cardiomyocytes (EC50 = 16.6 μM); induces bone morphological defects in mouse fetuses

Formal name: α-butyl-α-(2,4-dichlorophenyl)-1H-1,2,4-triazole-1-ethanol

Synonyms:  (±)-Hexaconazole

Molecular weight: 314.2

CAS: 79983-71-4

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Pesticides|Fungicides||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Cell Biology|Stem Cell Research|Differentiation||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Plant Biology|Phytoprotectants||Research Area|Toxicology|Environmental|Agriculture

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