A triterpenoid saponin with diverse biological activities; induces potassium release and hemolysis in mouse erythrocytes at 10 μg/ml; cytotoxic to N1E-115 neuroblastoma cells at low pH; induces proliferation of human embryonic fibroblasts in acidic medium

Hederoside D2 – 5 mg

Brand:
Cayman
CAS:
20853-58-1
Storage:
-20
UN-No:
Non-Hazardous - /

Hederoside D2 is a triterpenoid saponin originally isolated from C. robustum rhizome and roots and has diverse biological activities.{48429,48430} It induces potassium release and hemolysis in mouse erythrocytes in a pH-dependent manner when used at a concentration of 10 μg/ml.{48430} Hederoside D2 is cytotoxic to N1E-115 neuroblastoma cells at low pH. It induces proliferation of human embryonic fibroblasts in acidic medium, an effect that can be blocked by the calcium channel blockers verapamil (Item No. 14288), diltiazem, and nitrendipine (Item No. 17549).  

 

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SKU: 27507 - 5 mg Category:

Description

A triterpenoid saponin with diverse biological activities; induces potassium release and hemolysis in mouse erythrocytes at 10 μg/ml; cytotoxic to N1E-115 neuroblastoma cells at low pH; induces proliferation of human embryonic fibroblasts in acidic medium

Formal name: (3β,4α)-3-[(2-O-β-D-glucopyranosyl-α-L-arabinopyranosyl)oxy]-23-hydroxy-olean-12-en-28-oic acid

Synonyms:  Cauloside C|Fatsiaside D1

Molecular weight: 767

CAS: 20853-58-1

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Saponins||Product Type|Biochemicals|Natural Products|Terpenes||Research Area|Cancer|Cell Death

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