A selective

HA-130 – 10 mg

Brand:
Cayman
CAS:
1229652-21-4
Storage:
-20
UN-No:
Non-Hazardous - /

HA-130 is a reversible inhibitor of autotaxin, completely blocking the hydrolysis of the substrate bis-pNPP with an IC50 value of 28 nM.{18138} It does not affect the activity of any proteasomal protease or related enzymes. HA-130 rapidly decreases plasma lysophosphatidic acid levels in mice when given intravenously (1 nM/g).{18138} HA-130 has been used to investigate the role of autotaxin in cells and animals.{31823,31824,31825}  

 

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SKU: 10498 - 10 mg Category:

Description

A selective, reversible inhibitor of autotaxin, completely blocking the hydrolysis of the substrate bis-pNPP with an IC50 value of 28 nM; rapidly decreases plasma lysophosphatidic acid levels in mice when given intravenously (1 nM/g)

Formal name: B-​[3-​[[4-​[[3-​[(4-​fluorophenyl)​methyl]​-​2,​4-​dioxo-​5-​thiazolidinylidene]​methyl]​phenoxy]​methyl]​phenyl]​-boronic acid

Synonyms: 

Molecular weight: 463.3

CAS: 1229652-21-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Phosphatases||Product Type|Biochemicals|Small Molecule Inhibitors|Phosphodiesterases||Research Area

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