An inhibitor of PKA

HA-100 (hydrochloride) – 5 mg

Brand:
Cayman
CAS:
210297-47-5
Storage:
-20
UN-No:
Non-Hazardous - /

HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50s = 8, 12, and 4 µM, respectively).{24251} It less effectively blocks the activity of myosin light chain kinase (IC50 = 240 µM).{24251}  

 

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Description

An inhibitor of PKA, PKC, and PKG (IC50s = 8, 12, and 4 µM, respectively); less effectively blocks the activity of MLCK (IC50 = 240 µM)

Formal name: 5-(1-piperazinylsulfonyl)-isoquinoline, dihydrochloride

Synonyms:  C-1

Molecular weight: 350.3

CAS: 210297-47-5

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|PKA||Product Type|Biochemicals|Kinase Inhibitors|PKC||Product Type|Biochemicals|Kinase Inhibitors|PKD & PKG||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling|cAMP Signaling||Research Area|Cell Biology|Cell Signaling|cGMP Signaling

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