A peptide corresponding partly to the amino-terminus of the Aα chain and Bβ chain of fibrin; inhibits fibrin polymerization and ADP-induced platelet aggregation (IC50 = 3 mM)

H-Gly-Pro-Arg-Pro-OH (acetate) – 5 mg

Brand:
Cayman
CAS:
157009-81-9
Storage:
-20
UN-No:
Non-Hazardous - /

H-Gly-Pro-Arg-Pro-OH (GPRP) is a peptide corresponding partly to the amino terminus of the Aα chain and Bβ chain of fibrin. It inhibits the spontaneous polymerization of fibrin monomers and also inhibits ADP-induced platelet aggregation (IC50 = 3 mM).{33274,33275,33276} GPRP binds to the fibrinogen D domain, inhibiting the ability of fibrinogen to bind to the platelet membrane glycoprotein GPIIb/IIIa.{33274,33275}  

 

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Description

A peptide corresponding partly to the amino-terminus of the Aα chain and Bβ chain of fibrin; inhibits fibrin polymerization and ADP-induced platelet aggregation (IC50 = 3 mM)

Formal name: glycyl-L-prolyl-L-arginyl-L-proline, monoacetate

Synonyms:  GPRP

Molecular weight: 485.5

CAS: 157009-81-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Peptides||Research Area|Cardiovascular System|Blood|Acute Phase Reactants||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Blood|Serum Proteins

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