Description
Soluble guanylate cyclase is a heterodimeric enzyme, composed of α and β subunits, that synthesizes cGMP from GTP. The enzyme is activated by the binding of nitric oxide or carbon monoxide to the heme group of the enzyme.{1707} Chronic hypoxia upregulates soluble guanylate expression in rat lung.{7644} The α1 subunit contains 690-717 amino acids and has a molecular mass of 77-82 kDa.{4654,3536,3434} The cloned β1 subunit of guanylate cyclase from human, bovine, and rat sources contains 619 amino acids and has a molecular mass of approximately 70,000.{4654,3535,3531}
Synonyms: GUCY1A1|sGC α1 subunit
Immunogen: Peptide from the internal region of human protein
Formulation: 500 µl of Peptide affinity-purified antibody
Isotype:
Applications: WB and IHC
Origin: Animal/Rabbit
Stability: 365 days
Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Signaling|cGMP Signaling||Research Area|Endocrinology & Metabolism|Nutrient Sensing