A natural guanidine-taurine analog derived from taurine; competitively inhibits taurine uptake by sodium-dependent taurine transporters in rat hepatocytes (Ki = 1.75 mM); a competitive glycine receptor antagonist in mouse striatal neurons

Guanidinoethyl sulfonate – 500 mg

Brand:
Cayman
CAS:
543-18-0
Storage:
-20
UN-No:
Non-Hazardous - /

Guanidinoethyl sulfonate, also known as taurocyamine, is a natural guanidine-taurine analog derived from taurine. It is an intermediate of taurine and hypotaurine metabolism and is phosphorylated by taurocyamine kinase.{28666} Guanidinoethyl sulfonate competitively inhibits taurine uptake by sodium-dependent taurine transporters in rat hepatocytes (Ki = 1.75 mM).{28663} It also acts as a competitive glycine receptor antagonist in mouse striatal neurons.{28664} Plasma levels of guanidinoethyl sulfonate are significantly increased in patients with chronic renal failure.{28665}  

 

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Description

A natural guanidine-taurine analog derived from taurine; competitively inhibits taurine uptake by sodium-dependent taurine transporters in rat hepatocytes (Ki = 1.75 mM); a competitive glycine receptor antagonist in mouse striatal neurons

Formal name: 2-[(aminoiminomethyl)amino]-ethanesulfonic acid

Synonyms:  NSC 667063|Taurocyamine

Molecular weight: 167.2

CAS: 543-18-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Endocrinology & Metabolism

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