Description
GPR31 is a 319 amino acid G protein-coupled receptor (GPCR) that acts as the receptor for the arachidonic acid (Item No. 90010) metabolite 12(S)-HETE (Item No. 34570). Binding of 12(S)-HETE to GPR31 leads to the activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-κB pathways. The dysregulation of GPR31 has been implicated in diseases such as arthritis, Alzheimer’s disease, and prostate cancer.{19754}
Synonyms: 12(S)-HETE Receptor|12-(S)-hydroxy-5,8,10,14-Eicosatetraenoic Acid Receptor|12-HETER|G Protein-Coupled Receptor 31
Immunogen: A synthetic peptide from the N-terminal region of human GPR31
Formulation: 500 µl Peptide affinity-purified polyclonal antibody
Isotype:
Applications: ELISA, FC, and IF
Origin:
Stability: 365 days
Application|ELISA||Application|Flow Cytometry||Application|Immunofluorescence||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cancer||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease
