Description
GPR31 is a 319 amino acid G protein-coupled receptor (GPCR) that acts as the receptor for the arachidonic acid metabolite 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12(S)-HETE) (Item No. 34570). Binding of 12(S)-HETE to GPR31 leads to the activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-κB pathways. The dysregulation of GPR31 has been implicated in diseases such as arthritis, Alzheimer’s disease, and prostate cancer.{19754}
Synonyms: 12(S)-HETE Receptor|G Protein-Coupled Receptor 31
Immunogen: human GPR31 amino acids 288-298
Formulation: 500µl of peptide affinity purified antibody
Isotype:
Applications: ELISA, ICC, and WB
Origin:
Stability: 730 days
Application|ELISA||Application|Immunocytochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cancer||Research Area|Cell Biology|Cell Signaling|NF-κB Signaling||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors||Research Area|Immunology & Inflammation|Arthritis (Non-autoimmune)||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease
