Description
An MMP inhibitor (Kis = 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively); reduces 5-aza-2′-deoxycytidine-induced increases in MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, and MMP-14 expression in as well as cell invasion by AsPC-1, BxPC-3, Hs766T, MiaPaCa2, and PANC-1 cancer cells; inhibits TPA- and PdiBu-induced increases in ear thickness and epidermal hyperplasia in mice at 100 μg, topical
Formal name: (3R)-3-[[[(1S)-1-(1H-indol-3-ylmethyl)-2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]amino]carbonyl]-5-methyl-hexanoic acid
Synonyms:
Molecular weight: 463.6
CAS: 171347-75-4
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Immunology & Inflammation
