Precursor of PEA

Glycerophospho-N-Palmitoyl Ethanolamine – 1 mg

Brand:
Cayman
CAS:
100575-09-5
Storage:
-20
UN-No:
Non-Hazardous - /

N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. For example, arachidonoyl ethanolamide (AEA) is an endogenous neurotransmitter that evokes cellular responses by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). The different types of NAE are derived from glycerophospho-linked precursors by the activity of glycerophosphodiesterase 1 (GDE1).{15460} Glycerophospho-N-palmitoyl ethanolamine (GP-NPEA) is the metabolic precursor of palmitoyl ethanolamide (PEA). PEA is an endogenous cannabinoid found in brain, liver, and other mammalian tissues,{2415} that has potent anti-inflammatory activity in vivo.{16742} PEA has low affinity for peripheral cannabinoid (CB2) and no appreciable affinity for central cannabinoid (CB1),{1134} suggesting that its efficacy is through a different receptor.  

 

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SKU: 10011356 - 1 mg Category:

Description

Precursor of PEA, an endogenous CB found in brain, liver, and other mammalian tissues; PEA has potent anti-inflammatory activity in vivo

Formal name: mono(2,3-dihydroxypropyl)-mono[2-[(1-oxohexadecyl)amino]ethyl]ester phosphoric acid

Synonyms:  GP-NAE|GP-NPEA

Molecular weight: 453.6

CAS: 100575-09-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Fatty Amides||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Immunology & Inflammation||Research Area|Lipid Biochemistry|Endocannabinoid/Endocannabinoid-like||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors||Research Area|Neuroscience|Cannabinoid Research|Endocannabinoids

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