A glucosinolate that has been found in cruciferous plants such as L. sativum; reduces the number of HM1-IMSS E. histolytica trophozoites (IC50 = 20.4 µg/ml)

Glucotropaeolin (potassium salt) – 10 mg

Brand:
Cayman
CAS:
5115-71-9
Storage:
-20
UN-No:
Non-Hazardous - /

Glucotropaeolin is a glucosinolate that has been found in cruciferous plants such as L. sativum.{36729} It has antiprotozoal activity against HM1-IMSS E. histolytica, reducing the number of trophozoites with an IC50 value of 20.4 µg/ml.{36730} Dietary administration of glucotropaeolin (1,000 mg/kg), unlike administration of whole glucosinolate extract, does not induce the activity of anticarcinogenic mixed-function oxidases in rat large intestines.{36731} Glucotropaeolin is inactive against the fungi F. culmorum and does not have antitumor activity, however, it is metabolized into isothiocyanate products that have these activities.{36729,36732}  

 

Out of stock

Add to quotes
SKU: 21463 - Category:

Description

A glucosinolate that has been found in cruciferous plants such as L. sativum; reduces the number of HM1-IMSS E. histolytica trophozoites (IC50 = 20.4 µg/ml)

Formal name: 1-[N-(sulfooxy)benzeneethanimidate] 1-thio-β-D-glucopyranose, monopotassium salt

Synonyms:  Benzyl Glucosinolate

Molecular weight: 447.5

CAS: 5115-71-9

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Natural Products||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases

Related products

  • PtdIns-(3

    PtdIns-(3,4,5)-P3-biotin (sodium salt) – 100 µg

    The PtdIn phosphates play an important role in the generation and transduction of intracellular signals.{8344,4096,14518} PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.  

     

    Brand:
    Cayman
    SKU:10009531 - 100 µg

    Available on backorder

    Add to quotes
    View product page
  • A zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers

    1,2-Dipalmitoyl-sn-glycero-3-PC – 100 mg

    1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.{14480,24261,14478,14479} It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.{14478} Incorporation of glycosphingolipid antigens into DPPC-containing liposomes increases the immunogenicity of the antigens in mice.{14479}  

     

    Brand:
    Cayman
    SKU:10009473 - 100 mg

    Available on backorder

    Add to quotes
    View product page
  • PtdIns-(3

    PtdIns-(3,4,5)-P3-biotin (sodium salt) – 10 µg

    The PtdIn phosphates play an important role in the generation and transduction of intracellular signals.{8344,4096,14518} PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.  

     

    Brand:
    Cayman
    SKU:10009531 - 10 µg

    Available on backorder

    Add to quotes
    View product page
  • A powerful effector in both the TetR and revTetR transcriptional regulator systems

    Anhydrotetracycline (hydrochloride) – 500 mg

    The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression.{17508} Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to bind tetO and block transcription.{17509,17510} Anhydrotetracycline (hydrochloride) is a powerful effector in both the tetracycline repressor (TetR) and reverse TetR (revTetR) systems, binding the Tet repressor 35-fold more strongly than Tet.{17508,17511} Moreover, anhydrotetracycline poorly binds the 30S ribosomal subunit, compared to Tet,{17512} so it does not act as a general inhibitor of translation and is a poor antibiotic. Perhaps related to this, the concentration of anhydrotetracycline that inhibits eukaryotic cell growth is more than a 1,000-fold above the dose that alters transcription through TetR.{17508}  

     

    Brand:
    Cayman
    SKU:10009542 - 500 mg

    Available on backorder

    Add to quotes
    View product page