Description
Globotetraosylceramides (Item Nos. 24881) are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes.{43016} They act as receptors for the Shiga toxins Stx1, Stx2, and Stx2e, the cytotoxic protein pierisin-1, and parvovirus B19.{43017,43018,43019} Globotetraosylceramides increase the expression of proteins responsible for enamel deposition, including ameloblastin, amelogenin, and enamelin, in dental epithelial cells and activate the ERK and p38 MAPK signaling pathways.{43020} Levels of globotetraosylceramides are elevated in fibroblasts from patients with salt and pepper syndrome, a neurocutaneous condition characterized by intellectual disability and hyper- and hypo-pigmented skin.{43021} Globotetraosylceramide Polyclonal Antibody can be used for ELISA and TLC immunoblotting. [Matreya, LLC. Catalog No. 1960]
Synonyms: Globoside GL-4 Polyclonal Antibody
Immunogen: Purified globotetraosylceramide and complete Freund’s adjuvant
Formulation: A liquid
Isotype: IgG/IgM
Applications: ELISA and TLC immunoblotting
Origin:
Stability: 730 days
Application|ELISA||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Shigellosis||Research Area|Lipid Biochemistry|Sphingolipids