Description
A ginsenoside that has diverse biological activities; inhibits the growth of HeLa and MS751 cervical cancer cells (IC50s = ~2.5-10 μM) and induces apoptosis in a concentration-dependent manner; inhibits LPS-induced increases in IL-1β, TNF-α, COX-2, and iNOS protein levels in murine alveolar macrophages at 5 and 10 μM; inhibits LPS-induced increases in the number of neutrophils and protein levels of IL-1β, TNF-α, COX-2, and iNOS in lung in a mouse model of acute lung inflammation at 10 mg/kg; blocks STZ-induced increases in amyloid-β accumulation in the hippocampus and cerebral cortex and prevents STZ-induced decreases in step-through latency time in a passive avoidance foot-shock test in a rat model of STZ-induced Alzheimer’s disease ,,
Formal name: (3β,12β,20E)-12-hydroxydammara-20(22),24-dien-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
Synonyms:
Molecular weight: 767
CAS: 186763-78-0
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Ginsenosides||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease||Research Area|Neuroscience|Neuroprotection
