A panaxatriol saponin that has diverse in vitro and in vivo effects

Ginsenoside Re – 1 mg

Brand:
Cayman
CAS:
52286-59-6
Storage:
-20
UN-No:
Non-Hazardous - /

Ginsenosides are pharmacologically active natural constituents of ginseng and other plants of the genus Panax.{24877} Structurally, they are steroid glycosides derived from the triterpene squalene.{24877} Ginsenoside Re is a panaxatriol saponin that is more abundant in some Panax species (e.g., P. quinquefolium) than others.{24880} This ginsenoside has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions.{24880,25016,25015,25017} Ginsenoside Re improves the effectiveness of chemotherapeutic agents by decreasing the expression of Multidrug Resistance Protein 1 and inhibiting P-glycoprotein.{24878} Notably, this ginsenoside is converted to other forms in response to steaming or heating plant materials, leading to loss of activity.{24880}  

 

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Description

A panaxatriol saponin that has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions; improves the effectiveness of chemotherapeutic agents by decreasing the expression of Multidrug Resistance Protein 1 and inhibiting P-glycoprotein

Formal name: (6α)-20-(β-D-glucopyranosyloxy)-3β,12β-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside

Synonyms:  Chikusetsusaponin IVc|NSC 308877|Panaxoside Re|Sanchinoside Re

Molecular weight: 947.2

CAS: 52286-59-6

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Natural Products|Ginsenosides||Product Type|Biochemicals|Natural Products|Glycosides||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Cancer|Multidrug Resistance||Research Area|Cardiovascular System|Vasculature|Angiogenesis||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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