A ginsenoside with diverse biological activities; increases the proliferation of HHDPCs and HaCaT human keratinocytes at 0.01

Ginsenoside F2 – 1 mg

Brand:
Cayman
CAS:
62025-49-4
Storage:
-20
UN-No:
Non-Hazardous - /

Ginsenoside F2 is a ginsenoside that has been found in P. ginseng and has diverse biological activities.{52461,52462,52463} It increases the proliferation of human hair dermal papilla cells (HHDPCs) and HaCaT human keratinocytes when used at concentrations of 0.01, 0.1, and 1 μM.{52461} Ginsenoside F2 (0.5 and 2.5 mg/kg) induces hair growth and increases hair density following depilation in mice. It is cytotoxic to U373MG glioblastoma cells in vitro (IC50 = 50 μg/ml) and reduces tumor growth in a U373MG mouse xenograft model when administered at a dose of 35 mg/kg every other day.{52462} Ginsenoside F2 (1 mg/ear) reduces ear edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice.{52463} It is a human intestinal bacterial metabolite of ginsenoside Rb1 (Item No. 15319) via the intermediate ginsenoside Rd (Item No. 15329).{52464}  

 

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SKU: 23435 - 1 mg Category:

Description

A ginsenoside with diverse biological activities; increases the proliferation of HHDPCs and HaCaT human keratinocytes at 0.01, 0.1, and 1 μM; induces hair growth and increases hair density following depilation in mice at 0.5 and 2.5 mg/kg; cytotoxic to U373MG glioblastoma cells in vitro (IC50 = 50 μg/ml); reduces tumor growth in a U373MG mouse xenograft model at 35 mg/kg every other day; reduces TPA-induced ear edema in mice 1 mg/ear; a human intestinal bacterial metabolite of ginsenoside Rb1 via the intermediate ginsenoside Rd

Formal name: (3β,12β)-12-hydroxydammar-24-ene-3,20-diyl bis-β-D-glucopyranoside

Synonyms: 

Molecular weight: 785

CAS: 62025-49-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Ginsenosides||Research Area|Cancer|Cell Death||Research Area|Endocrinology & Metabolism|Bile Acids & Microbiome||Research Area|Immunology & Inflammation

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