A pyranone antibiotic that acts as a reversible

Germicidin B – 5 mg

Brand:
Cayman
CAS:
150973-78-7
Storage:
-20
UN-No:
Non-Hazardous - /

Germicidin B is a pyranone antibiotic originally derived from Streptomyces. It acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus Streptomyces at concentrations as low as 200 pM.{31633,31632} During germination, spores of Streptomyces excrete germicidin B along with other germicidin homologs, which inhibit germination of its own arthrospores.{31633,31632} At higher concentrations, germicidin can inhibit the porcine brain Na+/K+-dependent ATPase (ID50 = 100 µM) and prevent the germination of the cress L. sativum.{31633}  

 

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SKU: 20591 - Category:

Description

A pyranone antibiotic that acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus Streptomyces at concentrations as low as 200 pM

Formal name: 3-ethyl-4-hydroxy-6-(1-methylethyl)-2H-pyran-2-one

Synonyms: 

Molecular weight: 182.2

CAS: 150973-78-7

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|ATPases||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Immunology & Inflammation

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