A cyclic thiopeptide bacterial metabolite; active against a variety of Gram-positive bacteria (MICs = 0.2-4 µg/ml)

Geninthiocin A – 500 µg

Brand:
Cayman
CAS:
158792-27-9
Storage:
-20
UN-No:
Non-Hazardous - /

Geninthiocin A is a cyclic thiopeptide bacterial metabolite originally isolated from Streptomyces sp. DD84.{42770} It is active against a variety of Gram-positive bacteria (MICs = 0.2-4 µg/ml), the Gram-negative bacterium C. violaceum (MIC = 19 µg/ml), and the fungus M. hiemalis (MIC = 38 µg/ml).{42771} Geninthiocin A also induces tipA promoter transcription with a minimum induction concentration of 1.2 ng/ml.{42770}  

 

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SKU: 28125 - 500 µg Category:

Description

A cyclic thiopeptide bacterial metabolite; active against a variety of Gram-positive bacteria (MICs = 0.2-4 µg/ml), the Gram-negative bacterium C. violaceum (MIC = 19 µg/ml), and the fungus M. hiemalis (MIC = 38 µg/ml); induces tipA promoter transcription with a minimum induction concentration of 1.2 ng/ml

Formal name: L-threonyl-2-[(1Z)-1-amino-1-propen-1-yl]-4-oxazolecarbonyl-2,3-didehydroalanyl-3-methyl-L-threonyl-2-(1-aminoethenyl)-5-methyl-4-oxazolecarbonyl-2,3-didehydroalanyl-6-[2-(1-aminoethenyl)-4-oxazolyl]-5-(4-carboxy-2-thiazolyl)-2-pyridinecarbonyl-2,3-didehydroalanyl-2,3-didehydro-alaninamide (7→1)-lactam

Synonyms: 

Molecular weight: 1,132.10

CAS: 158792-27-9

Purity: ≥95%

Formulation: A powder

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