Description
Ganglioside GM2 asialo (asialo- GM2; Item No. 24629) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively.{40891} It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients.{40892} Ganglioside GM2 Asialo Polyclonal Antibody can be used for ELISA and TLC immunoblotting. [Matreya, LLC. Catalog No. 1951]
Synonyms:
Immunogen: Purified ganglioside GM2 asialo and complete Freund’s adjuvant
Formulation: A liquid
Isotype: IgG/IgM
Applications: ELISA and TLC immunoblotting
Origin:
Stability: 730 days
Application|ELISA||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Cholera||Research Area|Lipid Biochemistry|Sphingolipids||Research Area|Neuroscience|Neurodegenerative Disorders
