Description
Ganglioside GD1b (Item No. 19569) is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events.{31218} The concentration of ganglioside GD1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects.{31219} Ganglioside GD1b levels are positively correlated with pilocytic astrocytoma tumor grade, and GD1b has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas.{54530} Ganglioside GD1b Polyclonal Antibody can be used for ELISA and TLC immunoblotting applications. [Matreya, LLC. Catalog No. 1964]
Synonyms:
Immunogen: Purified ganglioside GD1b and complete Freund’s adjuvant
Formulation: 50 µl of polyclonal antibody to GD1b
Isotype: IgG/IgM
Applications: ELISA, TLC Immunoblotting
Origin:
Stability: 730 days
Application|ELISA||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cancer||Research Area|Lipid Biochemistry|Sphingolipids||Research Area|Neuroscience
