A reduced form of galactose; a toxic metabolite of galactose in humans; accumulates in the lens of patients with galactokinase deficiency-induced galactosemia

Galactitol – 100 g

Brand:
Cayman
CAS:
608-66-2
Storage:
-20
UN-No:
Non-Hazardous - /

Galactitol is a reduced form of galactose (Item No. 20890) that has been found in various plants, including C. aculeatus.{43179} It is a toxic metabolite of galactose in humans that accumulates in the lens of patients with galactokinase deficiency-induced galactosemia, leading to cataract formation.{43180} Galactitol also accumulates in a transgenic mouse model of galactokinase deficiency, however, it does not lead to the formation of cataracts even with administration of a high-galactose diet.{43181}  

 

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SKU: 25023 - 100 g Category:

Description

A reduced form of galactose; a toxic metabolite of galactose in humans; accumulates in the lens of patients with galactokinase deficiency-induced galactosemia, leading to cataract formation; accumulates in a transgenic mouse model of galactokinase deficiency but does not lead to cataract formation

Formal name: Galactitol

Synonyms:  Dulcitol|NSC 1944

Molecular weight: 182.2

CAS: 608-66-2

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Toxins||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Endocrinology & Metabolism|Carbohydrate Metabolism||Research Area|Endocrinology & Metabolism|Inborn Errors of Metabolism||Research Area|Neuroscience|Ophthalmology

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