Description
A phytotoxin; induces death of tomato plants from 0.1-0.2 μg/ml; induces permanent opening of leaf stomata and wilting in tobacco (N. tabacum), sorghum (S. bicolor), cucumber (C. sativa), lucerne (M. sativa), and pokeweed (P. Americana); binds to the preformed complex between plasma membrane H+-ATPase and a 14-3-3 protein in plants to stabilize and activate the enzyme; stabilizes eukaryotic 14-3-3 protein interactions with binding partners containing a C-terminal 14-3-3 recognition motif; stimulates cortical neurite outgrowth in a 14-3-3 protein-dependent manner (EC50 = 29 μM); topical administration to the injury site reduces collapse and retraction of severed axons in a mouse model of spinal cord injury
Formal name: (1S,4R,5R,6R,6aS,9S,10aR)-3-[(1S)-2-(acetyloxy)-1-methylethyl]-1,2,4,5,6,6a,7,8,9,10a-decahydro-1,5-dihydroxy-9-(methoxymethyl)-6,10a-dimethyldicyclopenta[a,d]cycloocten-4-yl 6-O-(1,1-dimethyl-2-propen-1-yl)-α-D-glucopyranoside, 3-acetate
Synonyms: NSC 113500
Molecular weight: 680.8
CAS: 20108-30-9
Purity: ≥98%
Formulation: A solid
Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Toxins||Research Area|Neuroscience||Research Area|Plant Biology|Phytotoxins
