Activates L-type Ca2+ channels (EC50 = 16 nM); prolongs action potential duration and increases contractility in guinea pig atria preparations (EC50 = 49 nM)

FPL 64176 – 1 mg

Brand:
Cayman
CAS:
120934-96-5
Storage:
-20
UN-No:
Non-Hazardous - /

FPL 64176 is a nondihydropyridine that activates L-type Ca2+ channels with an EC50 value of 16 nM.{31979,31977} It prolongs action potential duration and increases contractility in guinea pig atria preparations with an EC50 value of 49 nM.{31977,31978}  

 

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SKU: 20122 - Category:

Description

Activates L-type Ca2+ channels (EC50 = 16 nM); prolongs action potential duration and increases contractility in guinea pig atria preparations (EC50 = 49 nM)

Formal name: 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylic acid, methyl ester

Synonyms: 

Molecular weight: 347.4

CAS: 120934-96-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Activators||Research Area|Cardiovascular System|Heart|Myocardial Contractility||Research Area|Cardiovascular System|Vasculature|Vasoconstriction

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