A broad-spectrum antibiotic active against Gram-negative and Gram-positive bacteria (MIC90s = 4-32 µg/ml); enters cells via the glycerol-3-phosphate and hexose-6-phosphate transporters; inhibits UDP-GlcNAc enolpyruvyl transferase (MurA)

Fosfomycin Trometamol – 25 mg

Brand:
Cayman
CAS:
78964-85-9
Storage:
4
UN-No:
Non-Hazardous - /

Fosfomycin trometamol is a broad-spectrum antibiotic that is active against Gram-negative and Gram-positive bacteria with MIC90 values of 8, 32, 4, and 32 µg/mL for ESBL E. coli, carbapenemase-producing K. pneumoniae, P. mirabilis, and methicillin-resistant S. saprophyticus, respectively, in a broth microdilution assay.{36221} It is an inhibitor of uridine diphospho-N-acetyl-D-glucosamine enolpyruvyl transferase (MurA) that enters cells via the glycerol-3-phosphate and hexose-6-phosphate transporters.{36220,36222} Formulations containing fosfomycin trometamol have been used in the treatment of urinary tract infections.  

 

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SKU: 23632 - 25 mg Category:

Description

A broad-spectrum antibiotic active against Gram-negative and Gram-positive bacteria (MIC90s = 4-32 µg/ml); enters cells via the glycerol-3-phosphate and hexose-6-phosphate transporters; inhibits UDP-GlcNAc enolpyruvyl transferase (MurA)

Formal name: P-[(2R,3S)-3-methyl-2-oxiranyl]-phosphonic acid compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol

Synonyms:  Fosfomycin Tromethamine

Molecular weight: 259.2

CAS: 78964-85-9

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia

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