A calcium antagonist that acts as a potent dilator of peripheral vessels; reduces calcium fluxes in vascular smooth muscle by blocking both voltage-dependent calcium channels and receptor-operated channels

Flunarizine (hydrochloride) – 1 g

Brand:
Cayman
CAS:
30484-77-6
Storage:
22
UN-No:
Non-Hazardous - /

Flunarizine is a calcium antagonist that acts as a potent dilator of peripheral vessels without having calcium-blocking actions in the heart.{22485} It reduces calcium fluxes in vascular smooth muscle by blocking both voltage-dependent calcium channels and receptor-operated channels.{32557} Flunarizine also acts as a dopamine D2 receptor antagonist.{32558} Through its action as a dilator of peripheral vessels, flunarizine has a role in the prophylaxis of migraine headaches.{32559,32560}  

 

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Description

A calcium antagonist that acts as a potent dilator of peripheral vessels; reduces calcium fluxes in vascular smooth muscle by blocking both voltage-dependent calcium channels and receptor-operated channels

Formal name: 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-piperazine, dihydrochloride

Synonyms: 

Molecular weight: 477.4

CAS: 30484-77-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Neuroscience|Pain Research

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