Immunogen: Human fibrinogen (α chain) • Host: Mouse • Species Reactivity: (+) Human • Applications: WB • MW = 70 kDa

Fibrinogen (α chain) Monoclonal Antibody – 100 µg

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Cayman
Storage:

Fibrinogen is a hexameric glycoprotein that has roles in coagulation and hemostasis.{53514,53515} It is comprised of two sets of Aα, Bβ, and γ polypeptide chains encoded by FGA, FGB, and FGG, respectively, in humans.{53514} Fibrinogen is synthesized in hepatocytes and secreted into the plasma. Following thrombin-mediated cleavage of N-terminal fibrinopeptides from the Aα and Bβ chains, yielding the α and β chains, respectively, fibrinogen assembles into fibrin protofibrils and then mature fibers, which provide structure and viscoelasticity to blood clots.{53515,53516,53518} Mutations in FGA, FGB, or FGG have been found in patients with afibrinogenemia or hypofibrinogenemia.{53514} Elevated plasma fibrinogen levels are associated with an increased risk of cardiovascular disease.{53517} Immune complexes containing citrullinated fibrinogen have been found in patients with anti-citrullinated protein antibody-positive rheumatoid arthritis.{21643} Cayman’s Fibrinogen (α chain) Monoclonal Antibody can be used for Western blot (WB) applications. The antibody recognizes the α chain of fibrinogen at 70 kDa from human samples.  

 

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SKU: 18793 - 100 µg Category:

Description

Immunogen: Human fibrinogen (α chain) • Host: Mouse • Species Reactivity: (+) Human • Applications: WB • MW = 70 kDa

Synonyms: FBG|FG|FGA

Immunogen: Human fibrinogen (α chain)

Formulation: 100 µg of protein G-purified antibody

Isotype: IgG1

Applications: WB

Origin:

Stability: 365 days

Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Cardiovascular Diseases||Research Area|Immunology & Inflammation|Autoimmunity|Rheumatoid Arthritis

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