FFAR3 (GPR41) (C-Term) Polyclonal Antibody – 1 ea

Brand:
Cayman
Storage:

Antigen: peptide from the C-terminal region of human GPR41 • Host: rabbit • Cross Reactivity: (+) human GPR41 • Application(s): FC, IF, and WB  

 

SKU: 15726- 1 ea Category:

Description

GPR41 is a G protein-coupled receptor activated by short chain fatty acids (SCFAs).{25541,25605,25606} Several SCFAs have the potential to bind and activate GPR41, with pentanoate being the most potent agonist.{25605} GPR41 couples through the Pertussis toxin-sensitive Gi/o family and its expression has been described in adipose tissue and the colonic lumen.{25541,25605,25606} The activation of GPR41 induces an increase in intracellular Ca2+, ERK1/2 activation, and a decrease in intracellular cAMP.{25541,25605,25606} Activation of GPR41 may be involved in intestinal inflammation. The predicted size for GPR41 is 39 kDa. Cayman’s GPR41 (C-term) Polyclonal Antibody detects a 43 kDa band by western blot in cell lysates.


Synonyms: Free Fatty Acid Receptor 3|G Protein-Coupled Receptor 41

Immunogen: peptide from the C-terminal region of human GPR41

Formulation: Peptide affinity-purified polyclonal antibody

Isotype:

Applications: FC, IF, and WB

Origin:

Stability: 730 days


Application|Flow Cytometry||Application|Immunofluorescence||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Signaling|ERK/MAPK Signaling||Research Area|Immunology & Inflammation