Description
GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids.{13140,13139} Found predominantly in the β-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion.{14194,14741} Overexpression of GPR40 in mouse β cells leads to glucose intolerance suggesting a link between GPR40 expression and diabetes.{14194,14741} The receptor has also been identified as a possible mediator of oleate- and linoleate- stimulated proliferation of the human breast cancer cell line, MCF-7.{14742,13137} GPR40 has a calculated mass of 31.4 kDa bases on its amino acid sequence.
Synonyms: Free Fatty Acid Receptor 1|G Protein-Coupled Receptor 40
Immunogen: human GPR40
Formulation: 500 ul of peptide affinity-purified antibody
Isotype:
Applications: IHC and WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cancer||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity
