A sterol; an intermediate in cholesterol biosynthesis from lanosterol; found at high concentrations in mammalian ovarian follicular fluid; increases survival of human oocytes isolated from patients with PCOS; improves cytoplasmic maturation of immature rodent and porcine oocytes in vitro; promotes completion of meiotic maturation to metaphase II and increases the rate of successful IVF in isolated mouse oocytes

FF-MAS – 500 µg

Brand:
Cayman
CAS:
64284-64-6
Storage:
-20
UN-No:
Non-Hazardous - /

Follicular fluid meiosis-activating sterol (FF-MAS) is an intermediate in cholesterol biosynthesis from lanosterol (Item No. 19521) that is found at high concentrations in mammalian ovarian follicular fluid.{42473} It increases survival of human oocytes isolated from patients with polycystic ovarian syndrome (PCOS) and improves cytoplasmic maturation of immature rodent and porcine oocytes in vitro.{42474} FF-MAS promotes completion of meiotic maturation to metaphase II and increases the rate of successful in vitro fertilization (IVF) in isolated mouse oocytes.{42475} Formulations containing FF-MAS have been used to improve embryo quality and implantation rate during IVF.  

 

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SKU: 26093 - 500 µg Category:

Description

A sterol; an intermediate in cholesterol biosynthesis from lanosterol; found at high concentrations in mammalian ovarian follicular fluid; increases survival of human oocytes isolated from patients with PCOS; improves cytoplasmic maturation of immature rodent and porcine oocytes in vitro; promotes completion of meiotic maturation to metaphase II and increases the rate of successful IVF in isolated mouse oocytes,

Formal name: (3β,5α)-4,4-dimethyl-cholesta-8,14,24-trien-3-ol

Synonyms:  Follicular Fluid Meiosis-activating Sterol

Molecular weight: 410.7

CAS: 64284-64-6

Purity: ≥90%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Sterol Lipids

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