An internal standard for the quantification of fexofenadine by GC- or LC-MS

Fexofenadine-d10 (hydrochloride) – 1 mg

Brand:
Cayman
CAS:
1215821-44-5
Storage:
-20
UN-No:
Non-Hazardous - /

Fexofenadine-d10 is intended for use as an internal standard for the quantification of fexofenadine (Item No. 18191) by GC- or LC-MS. Fexofenadine is a histamine H1 receptor antagonist (Ki = 10 nM).{27483} It reverses contraction of isolated rat tracheal strips induced by acetyl-β-methylcholine (Item No. 23092).{36897} Fexofenadine inhibits expression of IL-8 in TNF-α-stimulated HCT116 and COLO 205 cells.{36898} Oral administration of fexofenadine (2 and 10 mg/kg) reduces severity of colitis and phospho-IκB kinase activation in a mouse model of colitis induced by dextran sulfate sodium (DSS; Item No. 23250).  

 

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SKU: 26115 - 1 mg Category:

Description

An internal standard for the quantification of fexofenadine by GC- or LC-MS

Formal name: 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl-d10)-1-piperidinyl]butyl]-α,α-dimethyl-benzeneacetic acid, monohydrochloride

Synonyms: 

Molecular weight: 548.2

CAS: 1215821-44-5

Purity: ≥99% deuterated forms (d1-d10)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Gastric Disease|Ulcerative Colitis

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