An NSAID; inhibits spontaneous and estradiol-stimulated PGF2α release in isolated rat uterine horns; reduces serum PGF2α levels in rats (10 mg/kg); reduces acetic acid-induced writhing and stretching as well as formalin-induced licking behaviors

Fenoprofen (calcium salt hydrate) – 10 g

Brand:
Cayman
CAS:
71720-56-4
Storage:
-20
UN-No:
Non-Hazardous - /

Fenoprofen is a non-steroidal anti-inflammatory drug (NSAID).{37334} It inhibits spontaneous and estradiol-stimulated prostaglandin F2α (PGF2α; Item No. 16010) release by 84% in isolated rat uterine horns when used at a concentration of 33 μM. Fenoprofen (10 mg/kg, i.p.) reduces serum PGF2α levels in rats. It reduces acetic acid-induced writhing and stretching as well as formalin-induced licking behaviors, indicating analgesic activity, however, it also induces formation of gastric lesions in mice, a common adverse effect associated with NSAID administration.{37335}  

 

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SKU: 23835 - 10 g Category:

Description

An NSAID; inhibits spontaneous and estradiol-stimulated PGF2α release in isolated rat uterine horns; reduces serum PGF2α levels in rats (10 mg/kg); reduces acetic acid-induced writhing and stretching as well as formalin-induced licking behaviors, indicating analgesic activity in mice

Formal name: α-methyl-3-phenoxy-benzeneacetic acid, calcium salt, dihydrate

Synonyms: 

Molecular weight: 279.3

CAS: 71720-56-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Immunology & Inflammation|Gastric Disease|Peptic Ulcers||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry

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