Description
A dopamine D3 receptor antagonist (Ki = 0.5 nM); selective for dopamine D3 receptors over dopamine D1, D2L, D2S, and D4 receptors (Kis = 8.8, 3.6, 2.6, and 0.34 µM, respectively) as well as 5-HT1A and 5-HT2 receptors (Kis = 0.36 and 2 µM, respectively); prevents memory impairment in the novel object recognition test in DAT-KD mice when administered prior to object learning from 1-10 mg/kg ,
Formal name: N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-benzo[b]thiophene-2-carboxamide
Synonyms:
Molecular weight: 462.4
CAS: 474432-66-1
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience|Behavioral Neuroscience|Bipolar Disorder