FAUC-365 – 1 mg

Brand:
Cayman
CAS:
474432-66-1
Storage:
-20
UN-No:
Non-Hazardous - /

FAUC-365 is a dopamine D3 receptor antagonist (Ki = 0.5 nM).{42635} It is selective for dopamine D3 receptors over dopamine D1, D2L, D2S, and D4 receptors (Kis = 8.8, 3.6, 2.6, and 0.34 µM, respectively) as well as the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT2 (Kis = 0.36 and 2 µM, respectively). FAUC-365 (1-10 mg/kg) prevents memory impairment in the novel object recognition test in dopamine transporter knockdown (DAT-KD) mice when administered prior to object learning.{42636}  

 

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SKU: 20457 - Category:

Description

A dopamine D3 receptor antagonist (Ki = 0.5 nM); selective for dopamine D3 receptors over dopamine D1, D2L, D2S, and D4 receptors (Kis = 8.8, 3.6, 2.6, and 0.34 µM, respectively) as well as 5-HT1A and 5-HT2 receptors (Kis = 0.36 and 2 µM, respectively); prevents memory impairment in the novel object recognition test in DAT-KD mice when administered prior to object learning from 1-10 mg/kg ,


Formal name: N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-benzo[b]thiophene-2-carboxamide

Synonyms: 

Molecular weight: 462.4

CAS: 474432-66-1

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience|Behavioral Neuroscience|Bipolar Disorder