A positive allosteric modulator of AMPA receptors (EC50 = >32 µM); enhances novel object memory (0.1 mg/kg

Farampator – 5 mg

Brand:
Cayman
CAS:
211735-76-1
Storage:
-20
UN-No:
Non-Hazardous - /

Farampator is a positive allosteric modulator of AMPA receptors that has an EC50 value greater than 32 µM for evoking glutamate currents in isolated pyramidal neurons.{39175} In rats, it enhances novel object recognition memory (0.1 mg/kg, p.o.) and attentional set-shifting (0.3 mg/kg, p.o.) and reverses a scopolamine-induced deficit in cued fear conditioning (0.1 mg/kg, p.o.).{39176}  

 

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Description

A positive allosteric modulator of AMPA receptors (EC50 = >32 µM); enhances novel object memory (0.1 mg/kg, p.o.) and attentional set-shifting (0.3 mg/kg, p.o.) in rats; reverses a scopolamine-induced deficit in cued fear conditioning (0.1 mg/kg, p.o.) in rats,

Formal name: 2,1,3-benzoxadiazol-5-yl-1-piperidinyl-methanone

Synonyms:  CX-691

Molecular weight: 231.3

CAS: 211735-76-1

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Activators||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory

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