Description
FABP4 is primarily expressed in adipocytes but is also expressed in activated macrophages, indicating that the protein plays a critical role in foam cell formation and thus atherosclerosis.{12288,12286} FABP4 was first purified from mouse 3T3-L1 adipocytes and then from human adipocytes and was named ALBP.{12291,12290} The expression of FABP4 is developmentally regulated by fatty acids, PPARγ agonists, and insulin.{12292,12285} In mice, deficiency of FABP4 prevents the development of hyperinsulinemia and insulin resistance in genetic and diet-induced obesity.{3423,12287}
Synonyms: A-FABP|Adipocyte FABP|ALBP|aP2|Fatty Acid Binding Protein 4
Immunogen: Synthetic peptide from the C-terminal region of human FABP4
Formulation: Peptide affinity-purified IgG
Isotype:
Applications: IF, IHC, and WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunohistochemistry||Application|Immunoprecipitation||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cardiovascular System|Cardiovascular Diseases|Atherosclerosis||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Lipid Biochemistry|Fatty Acids
