A linear pentapeptide that communicating cells produce and release

Extracellular Death Factor – 1 mg

Brand:
Cayman
CAS:
960129-66-2
Storage:
-20
UN-No:
Non-Hazardous - /

Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing. Extracellular death factor (EDF) is a linear pentapeptide that communicating cells produce and release, which upon reaching a sufficient concentration activates the cell death pathway in a subset of cells.{24994} It is sensitive to extreme pH, high temperatures, and other stressful conditions.{24994} At 2.5 ng/ml, EDF has been shown to facilitate mazEF-mediated cell death, significantly reducing population size in E. coli cultures.{24994}  

 

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Description

A linear pentapeptide that communicating cells produce and release, which upon reaching a sufficient concentration activates the cell death pathway in a subset of cells; facilitates mazEF-mediated cell death, significantly reducing population size in E. coli cultures at 2.5 ng/ml

Formal name: L-asparaginyl-L-asparaginyl-L-tryptophyl-L-asparaginyl-L-asparagine

Synonyms:  EDF

Molecular weight: 660.6

CAS: 960129-66-2

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics|Polypeptides||Product Type|Biochemicals|Peptides||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Quorum Sensing

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