A cell-permeable

Exo1 – 10 mg

Brand:
Cayman
CAS:
75541-83-2
Storage:
22
UN-No:
Non-Hazardous - /

Exo1 is a cell-permeable, reversible inhibitor of exocytosis (IC50 = 20 µM).{29668} It interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum by dissociating the GTPase activator ADP-ribosylation factor (ARF1) from Golgi membranes, which leads to a consequent collapse of the Golgi apparatus.{29668}  

 

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Description

A cell-permeable, reversible inhibitor of exocytosis (IC50 = 20 µM); interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum by dissociating the GTPase activator ARF1 from Golgi membranes

Formal name: 2-[(4-fluorobenzoyl)amino]-benzoic acid, methyl ester

Synonyms:  Exocytic Inhibitor 1|NSC 214045

Molecular weight: 273.3

CAS: 75541-83-2

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals||Research Area|Cell Biology|Cell Signaling|GTPases||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking

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