(+)-Evodiamine – 50 mg

Brand:
Cayman
CAS:
518-17-2
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Evodiamine is a natural indole alkaloid found in the fruits of Wu Zhu Yu, a plant used in traditional Chinese medicine. Studies involving evodiamine have demonstrated beneficial effects in cancer, obesity, inflammation, and many other conditions.{27591,27590,27592} It can act as an aryl hydrocarbon antagonist (Ki = 28 nM), activator of the transient receptor potential vanilloid 1 channel (EC50 = 45 nM), and inhibit signaling through NF-κB.{27591,27588,27589}  

 

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Description

A natural indole alkaloid with demonstrated beneficial effects in cancer, obesity, inflammation, and many other conditions; an AhR antagonist (Ki = 28 nM), activator of TRPV1 (EC50 = 45 nM), and inhibitor of signaling through NF-κB


Formal name: 8,13,13bS,14-tetrahydro-14-methyl-indolo[2′,3′:3,4]pyrido[2,1-b]quinazolin-5(7H)-one

Synonyms:  D-Evodiamine

Molecular weight: 303.4

CAS: 518-17-2

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Ion Channel Modulation|Activators||Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Natural Products|Alkaloids||Product Type|Biochemicals|Small Molecule Inhibitors|TNF-α/NF-κB Signaling||Research Area|Cancer|Cell Signaling|NF-κB Signaling||Research Area|Cancer|Transcription Factors|NF-κB||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Immunology & Inflammation