A secondary metabolite produced by some species of lichen that binds FAS-II enzymes to produce antibacterial and antiplasmodial effects; inhibits PfFabZ and PfFabI (IC50 = 10.7 and 36.1 µM

Evernic Acid – 250 mg

Brand:
Cayman
CAS:
537-09-7
Storage:
-20
UN-No:
Non-Hazardous - /

Evernic acid is a secondary metabolite produced by some species of lichen that can bind to allosteric sites on the protein surface of FAS-II enzymes and produce antibacterial and antiplasmodial effects.{28468} It inhibits two key plasmodial FAS-II enzymes PfFabZ and PfFabI (IC50 = 10.7 and 36.1 µM, respectively) but shows low efficacy against the malaria parasite P. berghei (IC50 = 77.3 µM).{28468}  

 

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Description

A secondary metabolite produced by some species of lichen that binds FAS-II enzymes to produce antibacterial and antiplasmodial effects; inhibits PfFabZ and PfFabI (IC50 = 10.7 and 36.1 µM, respectively) but shows low efficacy against the malaria parasite P. berghei (IC50 = 77.3 µM)

Formal name: 2-hydroxy-4-[(2-hydroxy-4-methoxy-6-methylbenzoyl)oxy]-6-methyl-benzoic acid

Synonyms:  NSC 81164

Molecular weight: 332.3

CAS: 537-09-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Parasitic Diseases|Malaria

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