Description
A tricyclic diterpene; inhibits early-stage adipogenesis of 3T3-L1 cells at 25 and 50 µM; inhibits proliferation of HL-60 cells in a concentration-dependent manner, as well as induces apoptosis and increases the expression of Fas and Fas ligand (FasL) and the activity of caspase-3 and caspase-8 in HL-60 cells; increases P-glycoprotein activity, reverses multi-drug resistance, and restores cytotoxicity of vinblastine, paclitaxel, and doxorubicin to MES/SA/Dx5 sarcoma cells
Formal name: benzeneacetic acid, (1aR,2’R,2E,4aR,6S,7S,7aR,8S,11aS)-4a,8-bis(acetyloxy)-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-4-oxospiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2′-oxiran]-7-yl ester
Synonyms:
Molecular weight: 552.7
CAS: 28649-59-4
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Cancer|Cell Death|Apoptosis
