A lichen metabolite and a derivative of lecanoric acid; inhibits the proliferation of human Hep-2 larynx carcinoma

Ethyl Orsellinate – 1 g

Brand:
Cayman
CAS:
2524-37-0
Storage:
-20
UN-No:
Non-Hazardous - /

Ethyl orsellinate is a lichen metabolite and a derivative of lecanoric acid (Item No. 22710) that has antiproliferative activities.{41961,41962} It inhibits the proliferation of human Hep-2 larynx carcinoma, MCF-7 breast cancer, and 786-0 kidney carcinoma cells, as well as B16-F10 murine melanoma and non-cancerous Vero cells (IC50s = 31.2, 70.3, 47.5, 64.8, and 28.1 µg/ml, respectively).{41962} Ethyl orsellinate is toxic to brine shrimp (A. salina) with an LC50 value of 495 µM.{41963}  

 

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Description

A lichen metabolite and a derivative of lecanoric acid; inhibits the proliferation of human Hep-2 larynx carcinoma, MCF-7 breast cancer, and 786-0 kidney carcinoma cells, as well as B16-F10 murine melanoma and non-cancerous Vero cells (IC50s = 31.2, 70.3, 47.5, 64.8, and 28.1 µg/ml, respectively); toxic to brine shrimp (LC50 = 495 µM)

Formal name: 2,4-dihydroxy-6-methyl-benzoic acid, ethyl ester

Synonyms:  NSC 149781

Molecular weight: 196.2

CAS: 2524-37-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Research Area|Cancer

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