An anticonvulsant; shortens the duration of the tonic extensor aspect of seizures induced by maximal electroshock in rats when administered at doses ranging from 500-1

Ethotoin – 10 mg

Brand:
Cayman
CAS:
86-35-1
Storage:
-20
UN-No:
Non-Hazardous - /

Ethotoin is a hydantoin anticonvulsant.{37306,37305} It shortens the duration of the tonic extensor aspect of seizures induced by maximal electroshock in rats when administered at doses ranging from 500-1,000 mg/kg.{37305} It also decreases the duration of the tonic phase of seizures at a dose of 1,000 mg/kg but does not affect the duration of the clonic phase at any dose.{37305} Ethotoin (20 mg/kg, i.p.) decreases serum cholesterol and triglyceride concentrations in mice to 67 and 60%, respectively, of control after 16 days of treatment.{37307} Formulations containing ethotoin have been used in the treatment of tonic-clonic and complex partial seizures.  

 

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SKU: 24022 - 10 mg Category:

Description

An anticonvulsant; shortens the duration of the tonic extensor aspect of seizures induced by maximal electroshock in rats when administered at doses ranging from 500-1,000 mg/kg; decreases the duration of the tonic phase of seizures at a dose of 1,000 mg/kg but does not affect the duration of the clonic phase at any dose; decreases serum cholesterol and triglyceride concentrations in mice to 67 and 60%, respectively, of control when administered at a dose of 20 mg/kg, i.p., for 16 days

Formal name: 3-ethyl-5-phenyl-2,4-imidazolidinedione

Synonyms:  (±)-Ethotoin

Molecular weight: 204.2

CAS: 86-35-1

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals||Research Area|Neuroscience|Seizure Disorders

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