An antimycobacterial compound active against M. tuberculosis (MICs = 0.3-1.25 µg/ml); activated via oxidation by flavin monooxygenase; inhibits InhA to block mycolic acid biosynthesis

Ethionamide – 5 g

Brand:
Cayman
CAS:
536-33-4
Storage:
4
UN-No:
Non-Hazardous - /

Ethionamide is an antimycobacterial compound that is active against M. tuberculosis (MICs = 0.3-1.25 µg/ml).{41216,41215} It is activated via oxidation by flavin monooxygenase and inhibits the InhA enzyme involved in mycolic acid biosynthesis.{41216} Formulations containing ethionamide have been used in the second-line treatment of multi-drug resistant tuberculosis.  

 

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SKU: 23714 - 5 g Category:

Description

An antimycobacterial compound active against M. tuberculosis (MICs = 0.3-1.25 µg/ml); activated via oxidation by flavin monooxygenase; inhibits InhA to block mycolic acid biosynthesis

Formal name: 2-ethyl-4-pyridinecarbothioamide

Synonyms:  NSC 255115

Molecular weight: 166.2

CAS: 536-33-4

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Tuberculosis

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